Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinazoline-2,4,6-Triamine SCHEMBL30050079 | 1.00 | DCPS (0.57) | DCPSDHFR | |
| SCHEMBL6094113 | 0.83 | DHFR (0.72) | DCPSDHFR | |
| SCHEMBL6679745 | 0.79 | HRH4 (0.58) | DCPSDHFR | |
| SCHEMBL5360039 | 0.79 | DCPS (0.53) | DCPSDHFR | |
| SCHEMBL27223540 | 0.79 | DCPS (0.53) | DCPSDHFR | |
| SCHEMBL29649743 | 0.79 | HTT (0.68) | DCPSDHFR | |
| SCHEMBL4755412 | 0.79 | DCPS (0.53) | DCPSDHFR | |
| SCHEMBL4358438 | 0.79 | HTT (0.68) | DCPSDHFR | |
| SCHEMBL3951373 | 0.79 | KDM4E (0.46) | DHFR | |
| SCHEMBL3335843 | 0.79 | HSP90AB1 (0.57) | DCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599783-B1 | N6-(FERROCENMETHYL)QUINAZOLIN-2,4,6-TRIAMIN (H2) AND THE DERIVATIVES AND PRODRUGS THEREOF AS ANTILEISHMANIAL, ANTIPROTOZOAL, ANTIPARASITIC AND ANTIMICROBIAL AGENTS | GALINDO SEVILLA NORMA DEL CARMEN (MX) | 2016-12-14 | — | — | EP | claimed |
| US-8664384-B2 | N6-(ferrocenmethyl)quinazolin-2,4,6-triamina (H2) and the derivatives and prodrugs thereof as antileishmanial, antiprotozoal, antiparasitic and antimicrobial agents | NORMA DEL CARMEN GALINDO SEVILLA (MX) | 2014-03-04 | — | — | US | claimed |
| EP-2599783-A1 | N6-(FERROCENMETHYL)QUINAZOLIN-2,4,6-TRIAMIN (H2) AND THE DERIVATIVES AND PRODRUGS THEREOF AS ANTILEISHMANIAL, ANTIPROTOZOAL, ANTIPARASITIC AND ANTIMICROBIAL AGENTS | Galindo Sevilla, Norma Del Carmen (MX) | 2013-06-05 | — | — | EP | claimed |
| US-20130109663-A1 | N6-(FERROCENMETHYL)QUINAZOLIN-2,4,6-TRIAMINA (H2) AND THE DERIVATIVES AND PRODRUGS THEREOF AS ANTILEISHMANIAL, ANTIPROTOZOAL, ANTIPARASITIC AND ANTIMICROBIAL AGENTS | GALINDO SEVILLA NORMA DEL CARMEN (MX) | 2013-05-02 | — | — | US | claimed |
| US-7060825-B2 | Process for synthesizing 6-quinazolinyl-ethyl-benzoyl and related antifolates | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2006-06-13 | — | — | US | claimed |
| WO-1999025327-A2 | SMALL MOLECULE INTERVENTION IN HIV-1 REPLICATION | WARNER-LAMBERT COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
| CN-119462528-A | 6, 8-Dinitroquinazoline-2, 4 (1H, 3H) -diketone energetic compound and synthetic method thereof | 南京理工大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-117736426-A | Polyether polyol and preparation method thereof, polyurethane rigid foam and preparation method thereof | 万华化学（宁波）容威聚氨酯有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| CN-109354825-B | High-temperature-resistant hot-melt benzoxazine resin and preparation method thereof | BEIJING COMPOSITE MATERIAL Co.,Ltd. (CN) | 2021-06-22 | — | — | CN | disclosed |
| EP-0253396-B1 | PROCESS FOR PREPARING 5,6-SUBSTITUTED-2,4-QUINAZOLINEDIAMINES AND INTERMEDIATES | WARNER-LAMBERT COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| CN-86100512-A | 2 of antitumor action is arranged, and 4-diamino-6-(N-methyl or formyl radical-replacement benzyl amino) quinoline derivatives is synthetic | — | 1987-09-02 | — | — | CN | disclosed |
| US-4677219-A | Substituted benzonitriles | WARNER-LAMBERT COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| US-4288595-A | ANTIBACTERIAL, ANTIMALARIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4233445-A | SYNERGISTIC WITH SULFA DRUGS AS BACTERICIDES AND ANTIPROTOZOA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4208520-A | BACTERICIDE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4118561-A | ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109663-A1 | N6-(FERROCENMETHYL)QUINAZOLIN-2,4,6-TRIAMINA (H2) AND THE DERIVATIVES AND PRODRUGS THEREOF AS ANTILEISHMANIAL, ANTIPROTOZOAL, ANTIPARASITIC AND ANTIMICROBIAL AGENTS | SLC40A1, H1-2, FECH | DCPS 186/4885DHFR 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.