SCHEMBL31735441

SCHEMBL31735441

COCCn1cc(Cl)c2cc(N)ccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.43
CNR2 P34972 4/20 0.38
CNR1 P21554 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NFATC1 O95644 1/20 0.37
GSK3B P49841 1/20 0.37
MAPT P10636 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
HBB P68871 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
P2RX7 Q99572 4/20 0.34
IL1B P01584 2/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3351946 0.88 DYRK1A (0.38) DYRK1ACNR2CNR1NPSR1NFATC1
SCHEMBL31735677 0.77 F2RL3 (0.46) CNR2CNR1MAPTMEN1KMT2A
SCHEMBL15134029 0.74 PRKCI (0.44) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL29492232 0.74 PRKCI (0.44) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL3350340 0.72 ALDH1A1 (0.53) CNR2CNR1NPSR1MEN1KMT2A
SCHEMBL3653449 0.71 PRKCI (0.54) DYRK1A
SCHEMBL20905568 0.71 P2RX7 (0.46) P2RX7IL1B
SCHEMBL13537209 0.70 CNR2 (0.41) DYRK1ACNR2CNR1NPSR1NFATC1
Hydrochloric Acid SCHEMBL20898498 0.70 P2RX7 (0.46) P2RX7IL1B
SCHEMBL3349651 0.70 HTR6 (0.41) DYRK1ACNR2CNR1NPSR1NFATC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed