SCHEMBL335062

SCHEMBL335062

C[C@H](N)c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2D6 P10635 1/20 0.47
NFKB1 P19838 1/20 0.47
PNMT P11086 1/20 0.47
ADRA2A P08913 3/20 0.46
ADRA2B P18089 3/20 0.46
ADRA2C P18825 3/20 0.46
ADRA1A P35348 2/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1B P35368 1/20 0.46
AOC3 Q16853 1/20 0.46
LMNA P02545 1/20 0.45
GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367357 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL29372643 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL128713 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL21538667 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL353568 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Iodide SCHEMBL25263727 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Ammonia Solution, Strong SCHEMBL19549028 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Iodide SCHEMBL21835042 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Hydrochloric Acid SCHEMBL607840 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Hydrochloric Acid SCHEMBL6251235 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1043 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595235-B2 Process for producing 4,5-dihydro-1H-pyrazoles and intermediates NOVO NORDISK A/S (DK) 2026-04-07 US claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 EP claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 EP claimed
US-20250078176-A1 ENVIRONMENTAL ATTRIBUTES FOR NITROGEN CONTAINING CHEMICALS BASF SE (DE) 2025-03-06 US claimed
US-12104106-B2 Compositions of chiral molecules and perovskite nanocrystals and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2024-10-01 US claimed
CN-118064400-B S-selective omega-aminotransferase mutant with high catalytic activity, and construction method and application thereof 中国科学院苏州生物医学工程技术研究所 2024-06-25 CN claimed
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA ZYDUS LIFESCIENCES LTD. (IN) 2024-05-30 US claimed
CN-118064400-A S-selective omega-aminotransferase mutant with high catalytic activity, and construction method and application thereof 中国科学院苏州生物医学工程技术研究所 2024-05-24 CN claimed
WO-2024064214-A2 SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-03-28 WO claimed
WO-2024028744-A1 TREATMENT FOR APLASTIC ANEMIA (AA) ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 WO claimed
EP-0763513-B1 Production of optically active 2-halo-1-(substituted phenyl)-ethanol and substituted styrene oxide NIHON NOHYAKU CO LTD (JP) 2001-11-14 EP claimed
US-6281391-B1 REACTING HYDROXYAMIDE COMPOUND WITH LITHIATING AGENT COMPRISING 4-METHYLTHIOPHENYLLITHIUM IN NON-REACTING SOLVENT TO FORM METHYLTHIOPHENYL-HYDROXYKETONE COMPOUND MERCK & CO., INC. 2001-08-28 US claimed
EP-0567438-B1 Optically pure cis-oxalato(trans-l-1,2-cyclohexanediamine)Pt(II) and process for resolving optical isomers of a platinum complex compound TANAKA PRECIOUS METAL IND (JP) 1999-01-13 EP claimed
US-5298642-A Process of optically resoluting optically active platinum complex compound TANAKA KIKINZOKU KOGYO K.K. (JP) 1994-03-29 US claimed
EP-0567438-A1 Optically pure cis-oxalato(trans-l-1,2-cyclohexanediamine)Pt(II) and process for resolving optical isomers of a platinum complex compound Tanaka Kikinzoku Kogyo K.K. (JP) 1993-10-27 EP claimed
EP-0213785-B1 METHOD FOR OPTICAL RESOLUTION OF DL-CYSTEINE AND (R,S)-1-(1-NAPHTHYL)ETHYLAMINE NIPPON RIKAGAKUYAKUHIN CO., LTD. (JP) 1990-02-07 EP claimed
US-4736060-A Method for optical resolution of DL-cysteine and (R,S)-1-(1-naphthyl) ethylamine NIPPON RIKAGAKUYAKUHIN CO., LTD. (JP) 1988-04-05 US claimed
EP-0213785-A1 Method for optical resolution of DL-cysteine and (R,S)-1-(1-naphthyl)ethylamine NIPPON RIKAGAKUYAKUHIN CO., LTD. (JP) 1987-03-11 EP claimed
US-4335057-A 4-(2',2,2'-Trihalogenoethyl)-cyclobutane-1-sulfonic acid salts with optically active bases CIBA-GEIGY CORPORATION (US) 1982-06-15 US claimed
US-4254279-A Ester resolution process FMC CORPORATION (US) 1981-03-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595235-B2 Process for producing 4,5-dihydro-1H-pyrazoles and intermediates PRMT1, SRM, CHRM1 ALDH1A1 1603/4885CYP1A2 222/4885CYP2C9 496/4885
US-20240173314-A1 TREATMENT OF SICKLE CELL ANAEMIA HBG1, HBB, HBG2 ALDH1A1 240/4885CYP1A2 794/4885CYP2C9 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.