SCHEMBL29367357

SCHEMBL29367357

C[C@@H](N)c1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2D6 P10635 1/20 0.47
NFKB1 P19838 1/20 0.47
PNMT P11086 1/20 0.47
ADRA2A P08913 3/20 0.46
ADRA2B P18089 3/20 0.46
ADRA2C P18825 3/20 0.46
ADRA1A P35348 2/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1B P35368 1/20 0.46
AOC3 Q16853 1/20 0.46
LMNA P02545 1/20 0.45
GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372643 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL128713 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL21538667 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL353568 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
SCHEMBL335062 1.00 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Iodide SCHEMBL25263727 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Ammonia Solution, Strong SCHEMBL19549028 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Iodide SCHEMBL21835042 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Hydrochloric Acid SCHEMBL607840 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2
Hydrochloric Acid SCHEMBL6251235 0.98 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059830-A Cinacalcet hydrochloride and preparation method thereof 江苏永安制药有限公司 2026-05-19 CN claimed
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) 2025-09-04 US claimed
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 EP claimed
CN-120192491-A Preparation method and application of chiral two-dimensional covalent organic framework material 湖南工程学院 2025-06-24 CN claimed
CN-120004740-A Synthesis method of cinacalcet hydrochloride 天津大学 2025-05-16 CN claimed
WO-2025099741-A1 PROCESS FOR THE PREPARATION OF NITROSAMINE FREE CINACALCET AND SALTS THEREOF MEGAFINE PHARMA (P) LTD. (IN) 2025-05-15 WO claimed
CN-117417285-B Isomanka key intermediate and preparation method thereof 苏中药业集团股份有限公司 2025-04-25 CN claimed
CN-119708400-A Preparation method and application of chiral aldehyde amine condensation covalent organic framework material 苏州大学 2025-03-28 CN claimed
CN-119592535-A Omega-aminotransferase ancestral enzyme mutant for efficiently catalyzing and synthesizing (R) -chiral amine compound and application thereof 浙江科技大学 2025-03-11 CN claimed
CN-119552185-A Method for recycling 4-BMA from 4-BMA mother liquor recycling material by using chiral amine 济南大学 2025-03-04 CN claimed
CN-115417803-A 5363 Synthesis method of intermediate (3R, 4S) -1-benzyloxycarbonyl-4-ethylpyrrolidine-3-carboxylic acid of Wu Pati Ni 四川同晟生物医药有限公司 2022-12-02 CN claimed
EP-4090654-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS Lupin Limited (IN) 2022-11-23 EP claimed
CN-115304729-A High-crystallinity chiral two-dimensional covalent organic framework material and preparation method thereof 中国科学院化学研究所 2022-11-08 CN claimed
CN-115181105-A Preparation method and application of R-type ketorolac 长春亿诺科医药科技有限责任公司 2022-10-14 CN claimed
WO-2022197182-A1 METHODS FOR PREPARING CYCLOOCTENES AND CONJUGATES THEREOF TAGWORKS PHARMACEUTICALS B.V. (NL) 2022-09-22 WO claimed
CN-114981253-A Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2022-08-30 CN claimed
CN-112321451-B Method for preparing cinacalcet hydrochloride drug intermediate 福建海西新药创制有限公司 2022-08-23 CN claimed
CN-114875472-A Organic-inorganic hybrid chiral perovskite helical structure micron sheet and preparation method and application thereof 河南大学 2022-08-09 CN claimed
CN-114409506-A Preparation method of diol compound 三门峡中达化工有限公司 2022-04-29 CN claimed
CN-111153832-B Preparation method of cinacalcet impurity 广州九植医药科技有限公司 2022-02-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276986-A1 PREPARATION METHOD FOR CHIRAL PYRROLE DERIVATIVE AND INTERMEDIATE THEREOF PIN1, DHPS, PPOX ALDH1A1 763/4885CYP1A2 286/4885CYP2C9 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.