Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30069509 | 1.00 | SIRT1 (0.39) | SIRT1MAOAMAOBKLK5MAPT | |
| SCHEMBL28990331 | 0.72 | MAOB (0.43) | SIRT1MAOAMAOBKLK5MEN1 | |
| SCHEMBL3345089 | 0.72 | MAOB (0.43) | SIRT1MAOAMAOBKLK5MEN1 | |
| SCHEMBL28988620 | 0.72 | ACHE (0.48) | SIRT1MAOAMAOBKLK5PPARG | |
| SCHEMBL4467512 | 0.72 | ANPEP (0.47) | SIRT1MAOAMAOBKLK5PPARG | |
| SCHEMBL2885515 | 0.72 | MAOA (0.43) | SIRT1MAOAMAOBKLK5MEN1 | |
| SCHEMBL31185920 | 0.72 | ANPEP (0.47) | SIRT1MAOAMAOBKLK5PPARG | |
| SCHEMBL8927781 | 0.72 | ACHE (0.48) | SIRT1MAOAMAOBKLK5PPARG | |
| SCHEMBL15147104 | 0.72 | ACHE (0.48) | SIRT1MAOAMAOBKLK5PPARG | |
| SCHEMBL29629339 | 0.72 | ACHE (0.48) | SIRT1MAOAMAOBKLK5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203214-A1 | Synthesis Of Chromanones | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | US | claimed |
| WO-2004103985-A2 | DERIVATIVES OF FUSAROCHROMANONE AS THERAPEUTIC AGENTS | UNIVERSITY OF SOUTH CAROLINA (US) | 2004-12-02 | — | — | WO | claimed |
| CN-115322208-B | 2-aminothiazole derivative and preparation method and medical application thereof | 中国药科大学 | 2023-04-11 | — | — | CN | disclosed |
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203214-A1 | Synthesis Of Chromanones | MAP3K6, MAP3K8, MAP3K1 | SIRT1 1087/4885MAOA 1648/4885MAOB 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.