Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | BMP1 | P13497 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647871 | 0.87 | LDHA (0.55) | ACELDHAITGB1ITGA4ENPP2 | |
| SCHEMBL3783037 | 0.79 | ENPP2 (0.42) | LDHAITGB1ITGA4ENPP2AKR1C3 | |
| SCHEMBL3787450 | 0.78 | ENPP2 (0.45) | LDHAITGB1ITGA4ENPP2AKR1C3 | |
| SCHEMBL19953751 | 0.78 | PTPRB (0.55) | LDHAITGB1ITGA4 | |
| SCHEMBL27801722 | 0.77 | MME (0.54) | LDHA | |
| SCHEMBL27790965 | 0.77 | TBXAS1 (0.48) | ACEITGB1ITGA4ENPP2AKR1C3 | |
| SCHEMBL3351530 | 0.76 | ENPP2 (0.40) | ACELDHAITGB1ITGA4ENPP2 | |
| SCHEMBL19953752 | 0.76 | LDHA (0.47) | ACELDHAITGB1ITGA4ENPP2 | |
| SCHEMBL19899914 | 0.76 | SLC7A5 (0.61) | TDP1ALDH1A1PTGS2 | |
| SCHEMBL19899916 | 0.76 | SLC7A5 (0.61) | TDP1ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |