Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808717 | 0.83 | SIGMAR1 (0.61) | HTR7P2RX7NOS3NOS1SIGMAR1 | |
| SCHEMBL13537275 | 0.80 | HTR7 (0.52) | HTR7P2RX7NOS3NOS1 | |
| SCHEMBL31461321 | 0.80 | HTR7 (0.64) | HTR7NOS3NOS1 | |
| SCHEMBL1122373 | 0.80 | HTR7 (0.57) | HTR7NOS3NOS1 | |
| SCHEMBL27812843 | 0.79 | CDK4 (0.44) | — | |
| SCHEMBL12253689 | 0.78 | HTR7 (0.56) | HTR7NOS3NOS1 | |
| SCHEMBL7805927 | 0.78 | HTR7 (0.50) | HTR7P2RX7 | |
| SCHEMBL3356709 | 0.78 | HTR7 (0.79) | HTR7P2RX7 | |
| SCHEMBL429679 | 0.77 | NOS3 (0.48) | HTR7NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL8021825 | 0.77 | HTR7 (0.49) | HTR7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |