Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733940 | 0.84 | STAT3 (0.51) | STAT3ATMKDM4ELDHAKMT2A | |
| SCHEMBL3348404 | 0.83 | STAT3 (0.65) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL5192260 | 0.81 | STAT3 (0.57) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL3346294 | 0.79 | STAT3 (0.56) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL29965330 | 0.79 | LDHA (0.60) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL29378321 | 0.79 | LDHA (0.60) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL31165204 | 0.79 | STAT3 (0.46) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL22445062 | 0.78 | STAT3 (0.57) | STAT3ATMKDM4ELDHACYP19A1 | |
| SCHEMBL5580783 | 0.78 | KMT2A (0.48) | KMT2AALDH1A1 | |
| SCHEMBL27673600 | 0.78 | STAT3 (0.71) | STAT3ATMKDM4ECYP19A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |