Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 7/20 | 0.55 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760081 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HDAC3HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7220026 | 0.98 | KDM4E (0.57) | KDM4EALDH1A1HDAC3HDAC1HDAC8 | |
| SCHEMBL2795026 | 0.89 | HTR7 (0.63) | KDM4EALDH1A1HDAC3HDAC1HDAC8 | |
| SCHEMBL4229926 | 0.87 | HTR7 (0.64) | HDAC3HDAC1HDAC8NCOR2HTR7 | |
| Hydrochloric Acid SCHEMBL31687556 | 0.87 | HTR7 (0.61) | HTR7HTR1ADRD3HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL4255618 | 0.87 | HTR7 (0.61) | HTR7HTR1ADRD3HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL7982174 | 0.87 | HTR7 (0.61) | HTR7HTR1ADRD3HTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL4222983 | 0.86 | HTR7 (0.62) | HDAC3HDAC1HDAC8NCOR2HTR7 | |
| SCHEMBL4225899 | 0.86 | HTR7 (0.62) | HDAC3HDAC1HDAC8NCOR2HTR7 | |
| Hydrochloric Acid SCHEMBL4224319 | 0.86 | HTR7 (0.62) | HDAC3HDAC1HDAC8NCOR2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
| US-20240109917-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2024-04-04 | — | — | US | disclosed |
| CN-117642397-A | Modified proteins and protein binders | 上海睿跃生物科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-11807622-B2 | TLR 9 inhibitors | INSILICO MEDICINE IP LIMITED (HK) | 2023-11-07 | — | — | US | disclosed |
| US-11807622-B2 | TLR 9 inhibitors | INSILICO MEDICINE IP LIMITED (HK) | 2023-11-07 | — | — | US | disclosed |
| EP-4267585-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | Actelion Pharmaceuticals Ltd (CH) | 2023-11-01 | — | — | EP | disclosed |
| CN-116768855-A | Aromatic amino acid compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-08-31 | — | — | US | disclosed |
| EP-4188919-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | Etat Français représenté par la Direction Centrale Du Service de Santé des Armées (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-20230121302-A1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | VERSITECH LIMITED (CN) | 2023-04-20 | — | — | US | disclosed |
| WO-2001094368-A1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-12-13 | — | — | WO | disclosed |
| EP-0732333-B1 | Indazolecarboxamides | LILLY CO ELI (US) | 2001-08-01 | — | — | EP | disclosed |
| US-5817676-A | 5-HT4 RECEPTOR ANTAGONISTS, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5798367-A | ANTAGONIZE 5-HYDROXYTRYPTAMINE RECEPTOR IN GASTROINTESTINAL TRACT OR GENITOURINARY TRACT | ELI LILLY AND COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| US-5654320-A | SEROTONIN RECEPTOR ANTAGONIST | ELI LILLY AND COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| WO-1996033713-A1 | INDAZOLECARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1996-10-31 | — | — | WO | disclosed |
| EP-0732333-A1 | Indazolecarboxamides | ELI LILLY AND COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5294621-A | Thieno tetrahydropyridines useful as class III antiarrhythmic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-4197243-A | ANTIPSYCHOTICS, STRONG CNS DEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4097487-A | CNS DEPRESSANTS, ANTIPSYCHOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270750-A1 | CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS | BCHE, ACHE, CHAT | KDM4E 1130/4885ALDH1A1 239/4885HDAC3 1127/4885 |
| US-20230121302-A1 | METHODS OF IRON CATALYZED C-H BOND AMINATION | FTH1, FECH, HCCS | KDM4E 2150/4885ALDH1A1 938/4885HDAC3 138/4885 |
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | KDM4E 1056/4885ALDH1A1 2985/4885HDAC3 801/4885 |
| US-11807622-B2 | TLR 9 inhibitors | TLR9, TLR1, TLR7 | KDM4E 943/4885ALDH1A1 4348/4885HDAC3 558/4885 |
| US-20240109917-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | PDGFRA, PDGFRB, ABL1 | KDM4E 2700/4885ALDH1A1 916/4885HDAC3 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.