Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 3/20 | 0.31 |
| ▸ | NOS1 | P29475 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352017 | 1.00 | PRKCI (0.34) | PRKCIMAPTALDH1A1GFERKDM4E | |
| SCHEMBL13537376 | 1.00 | PRKCI (0.34) | PRKCIMAPTALDH1A1GFERKDM4E | |
| SCHEMBL13537317 | 0.80 | HTR1A (0.36) | SIGMAR1SCN9A | |
| SCHEMBL3358552 | 0.78 | HTR7 (0.45) | MAPTALDH1A1SIGMAR1 | |
| SCHEMBL24110302 | 0.77 | SCD (0.37) | SCN9A | |
| SCHEMBL3354536 | 0.76 | OPRM1 (0.36) | PRKCIMAPTALDH1A1GFERKDM4E | |
| SCHEMBL24110275 | 0.76 | SCD (0.41) | SCN9A | |
| SCHEMBL3354541 | 0.76 | OPRM1 (0.36) | PRKCIMAPTALDH1A1GFERKDM4E | |
| SCHEMBL3358911 | 0.76 | OPRM1 (0.36) | PRKCIMAPTALDH1A1GFERKDM4E | |
| SCHEMBL24110299 | 0.74 | HTR2A (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |