Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 8/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354536 | 1.00 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3354541 | 1.00 | OPRM1 (0.36) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL13537315 | 0.80 | HTR1A (0.44) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3352865 | 0.79 | HTR1D (0.51) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3357769 | 0.78 | NOS3 (0.44) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL12459068 | 0.78 | KDM4C (0.39) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3351996 | 0.78 | ASH1L (0.43) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3352705 | 0.78 | IRAK4 (0.44) | SLC6A4IRAK4ALDH1A1MAPT | |
| SCHEMBL3353152 | 0.78 | IRAK4 (0.44) | SLC6A4IRAK4ALDH1A1MAPT | |
| SCHEMBL3352022 | 0.76 | PRKCI (0.34) | OPRM1OPRD1OPRK1PRKCINOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |