Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80263 | 0.89 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1GAALMNAPOLB | |
| Benzene SCHEMBL10992898 | 0.82 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1GAALMNAPOLB | |
| SCHEMBL6805430 | 0.80 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1GAALMNAPOLB | |
| SCHEMBL1122035 | 0.80 | AKR1C3 (0.52) | ALDH1A1ELANEL3MBTL1GAALMNA | |
| SCHEMBL18979666 | 0.77 | CES1 (0.66) | ALDH1A1ELANEL3MBTL1GAALMNA | |
| SCHEMBL3687049 | 0.77 | AKR1B1 (0.61) | ALDH1A1L3MBTL1GAALMNAMAPT | |
| SCHEMBL29676820 | 0.77 | AKR1B1 (0.61) | ALDH1A1L3MBTL1GAALMNAMAPT | |
| SCHEMBL16162416 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ELANEL3MBTL1GAALMNA | |
| Benzophenone SCHEMBL6910177 | 0.74 | ALDH1A1 (0.67) | ALDH1A1ELANEL3MBTL1GAALMNA | |
| SCHEMBL7150622 | 0.74 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061526-B1 | COATED MEDICAL DEVICE | DSM IP ASSETS BV (NL) | 2015-07-29 | — | — | EP | disclosed |
| US-8828546-B2 | Coated medical device | DSM IP ASSETS B.V. (NL) | 2014-09-09 | — | — | US | disclosed |
| US-20140180221-A1 | COATED MEDICAL DEVICE | DSM IP ASSETS B.V. (NL) | 2014-06-26 | — | — | US | disclosed |
| US-20100114042-A1 | COATED MEDICAL DEVICE | DSM IP ASSETS B.V. (NL) | 2010-05-06 | — | — | US | disclosed |
| EP-2061526-A2 | COATED MEDICAL DEVICE | DSMIP Assets B.V. (NL) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008031595-A2 | COATED MEDICAL DEVICE | DSM IP ASSETS B.V. (NL) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100114042-A1 | COATED MEDICAL DEVICE | PNN, F9, PTN | ALDH1A1 4379/4885ELANE 911/4885L3MBTL1 4387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.