Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378582 | 0.88 | RORC (0.33) | RORCCNR2 | |
| SCHEMBL3345234 | 0.84 | CNR2 (0.34) | CNR2 | |
| SCHEMBL3347085 | 0.81 | RORC (0.40) | RORCCNR2PDE4D | |
| SCHEMBL3347090 | 0.81 | RORC (0.40) | RORCCNR2PDE4D | |
| SCHEMBL3379792 | 0.80 | RORC (0.38) | RORCCNR2PDE4D | |
| SCHEMBL3379795 | 0.80 | RORC (0.38) | RORCCNR2PDE4D | |
| SCHEMBL3106752 | 0.78 | OPRM1 (0.35) | — | |
| SCHEMBL3111829 | 0.71 | KCNH2 (0.38) | — | |
| SCHEMBL3331892 | 0.70 | KCNH2 (0.37) | — | |
| SCHEMBL3110372 | 0.70 | ELANE (0.33) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045987-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUIN0LIN-2-0NES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |