Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497313 | 0.90 | GAA (0.75) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL30497269 | 0.87 | GAA (0.70) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3352200 | 0.85 | GAA (0.61) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3357708 | 0.83 | ALDH1A1 (0.58) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3356727 | 0.82 | GAA (0.49) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4288972 | 0.82 | GAA (1.00) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3356346 | 0.80 | DDB1 (0.49) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3354425 | 0.78 | GAA (0.45) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL29784271 | 0.77 | GAA (0.86) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4437592 | 0.77 | GAA (0.86) | GAAHSD17B10HPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |