SCHEMBL3352386

SCHEMBL3352386

Cc1ccc(Nc2cccc3cccnc23)cc1.Cc1ccc(Nc2cccc3cccnc23)cc1.[Cd]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.59
SHMT2 P34897 1/20 0.58
KMT2A Q03164 5/20 0.57
TDP1 Q9NUW8 5/20 0.57
SLC40A1 Q9NP59 5/20 0.57
MAPT P10636 4/20 0.57
ALDH1A1 P00352 2/20 0.57
HTT P42858 2/20 0.57
LMNA P02545 2/20 0.57
MITF O75030 1/20 0.57
S1PR4 O95977 1/20 0.57
S1PR1 P21453 1/20 0.57
AGTR1 P30556 1/20 0.57
OPRK1 P41145 1/20 0.57
CKS1B P61024 1/20 0.57
SKP2 Q13309 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
MEN1 O00255 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22926774 0.98 HDAC6 (0.61) HDAC6SHMT2KMT2ATDP1SLC40A1
SCHEMBL1144237 0.97 HDAC6 (0.59) HDAC6SHMT2KMT2ATDP1SLC40A1
SCHEMBL3292874 0.97 HDAC6 (0.59) HDAC6SHMT2KMT2ATDP1SLC40A1
SCHEMBL28024173 0.84 KMT2A (0.55) HDAC6SHMT2KMT2ATDP1SLC40A1
SCHEMBL341142 0.83 SLC40A1 (0.62) HDAC6KMT2ATDP1SLC40A1MAPT
SCHEMBL24522570 0.82 MAPT (0.67) HDAC6KMT2ATDP1SLC40A1MAPT
SCHEMBL9702768 0.82 HDAC6 (0.65) HDAC6KMT2ATDP1SLC40A1MAPT
SCHEMBL1008580 0.81 GLO1 (0.61) HDAC6SHMT2KMT2ATDP1SLC40A1
SCHEMBL379216 0.80 GLO1 (0.59) HDAC6KMT2ATDP1SLC40A1MAPT
SCHEMBL28232978 0.78 SLC40A1 (0.61) HDAC6SLC40A1MAPTGLO1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9281498-B2 Organic EL device KANEKA CORPORATION (JP) 2016-03-08 US disclosed
US-20130249390-A1 ORGANIC EL DEVICE KANEKA CORPORATION (JP) 2013-09-26 US disclosed
US-7732249-B2 Organic EL light emitting display device and method of manufacturing the same KABUSHIKI KAISHA TOSHIBA (JP) 2010-06-08 US disclosed
US-7511422-B2 Organic electroluminescent element with specific structure connecting luminescent regions and organic electroluminescent device including the same KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2009-03-31 US disclosed
US-20070243651-A1 Organic EL light emitting display device and method of manufacturing the same MIZUNO YUKITAMI 2007-10-18 US disclosed
US-7247886-B2 Organic EL light emitting display device and method of manufacturing the same KABUSHIKI KAISHA TOSHIBA (JP) 2007-07-24 US disclosed
EP-1521305-A2 Organic electroluminescent element and organic electroluminescent device including the same Kabushiki Kaisha Toyota Jidoshokki (JP) 2005-04-06 EP disclosed
US-20050062050-A1 Organic EL light emitting display device and method of manufacturing the same KABUSHIKI KAISHA TOSHIBA. 2005-03-24 US disclosed