Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MECP2 | P51608 | 1/20 | 0.44 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232978 | 0.85 | SLC40A1 (0.61) | GLO1HDAC6SLC40A1MAPTTRPV1 | |
| SCHEMBL22926774 | 0.83 | HDAC6 (0.61) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL1144237 | 0.81 | HDAC6 (0.59) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL3352386 | 0.81 | HDAC6 (0.59) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL3292874 | 0.81 | HDAC6 (0.59) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL341142 | 0.80 | SLC40A1 (0.62) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL24522570 | 0.80 | MAPT (0.67) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL9702768 | 0.80 | HDAC6 (0.65) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL379216 | 0.78 | GLO1 (0.59) | GLO1HDAC6ALOX15HTTPOLB | |
| SCHEMBL13762082 | 0.77 | HDAC6 (0.73) | GLO1HDAC6HTTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009082-B1 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-1801189-B1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2012-11-07 | — | — | EP | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |
| US-7683017-B2 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC (US) | 2010-03-23 | — | — | US | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| EP-2009082-A2 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20080318815-A1 | SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF A NITRO-SUBSTITUTED DIARYLAMINE AND A DAIRYLAMINE | CHEVRON ORONITE COMPANY LLC | 2008-12-25 | — | — | US | disclosed |
| EP-1801104-A2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801104-A2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801189-A2 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | AHR, ARNT, HRH2 | GLO1 1660/4885HDAC6 367/4885ALOX15 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.