Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3352462

C[Si]1(C)c2cccc3c2C([Ti+2]C2c4ccccc4-c4cccc1c42)c1ccccc1-3.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6911931 0.77 GPR3 (0.32) GPR3POLB
Hydrochloric Acid SCHEMBL2749840 0.77 GPR3 (0.32) GPR3POLB
SCHEMBL8373493 0.75 GPR3 (0.33) GPR3
SCHEMBL7766798 0.73 GPR3 (0.32) GPR3POLB
Hydrochloric Acid SCHEMBL5616348 0.73 HTR2A (0.39) GPR3POLB
Hydrochloric Acid SCHEMBL5616477 0.72 HTR1A (0.38)
Hydrochloric Acid SCHEMBL3354015 0.70 GPR3 (0.31) GPR3POLB
SCHEMBL7930860 0.70 GPR3 (0.30) GPR3
SCHEMBL7930904 0.70 BCHE (0.31) GPR3
SCHEMBL7770500 0.70 GPR3 (0.30) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410231-B2 Production process of olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-02 US disclosed
US-20100029868-A1 PRODUCTION PROCESS OF OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-04 US disclosed
EP-0996647-B1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS TECH OY (FI) 2004-09-08 EP disclosed
EP-0996647-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 2000-05-03 EP disclosed
WO-1999003897-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 1999-01-28 WO disclosed