SCHEMBL33525287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2243716	1.00	ALDH1A1 (0.46)	ALDH1A1MAPTGAATSHRPOLB
	SCHEMBL28297001	0.86	ALDH1A1 (0.37)	ALDH1A1MAPTGAATSHRPOLB
	SCHEMBL7533909	0.86	ADRA2B (0.41)	ALDH1A1MAPTGAATSHRPOLB
	SCHEMBL21995029	0.84	TSHR (0.46)	ALDH1A1MAPTGAATSHRNPSR1
	SCHEMBL8763037	0.84	TSHR (0.46)	ALDH1A1MAPTGAATSHRNPSR1
	SCHEMBL14390806	0.83	CYP3A4 (0.44)	ALDH1A1TSHRPOLBSIGMAR1
	SCHEMBL4625754	0.83	MAPT (0.46)	ALDH1A1MAPTGAATSHRPOLB
	SCHEMBL11286222	0.83	TSHR (0.44)	ALDH1A1MAPTGAATSHRNPSR1
	SCHEMBL23396676	0.82	TSHR (0.41)	ALDH1A1MAPTTSHRPOLBLMNA
	Quinoline SCHEMBL28295243	0.81	ALDH1A1 (0.49)	ALDH1A1MAPTPOLBHDAC3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.