SCHEMBL33525657

SCHEMBL33525657

CC(C)(Cn1nc(C(F)(F)F)cc1Br)NC(=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 2/20 0.43
TSHR P16473 1/20 0.43
CARM1 Q86X55 1/20 0.43
AAK1 Q2M2I8 2/20 0.39
MGLL Q99685 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
MAPT P10636 3/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CTSS P25774 1/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
RECQL P46063 1/20 0.37
GRN P28799 1/20 0.37
SORT1 Q99523 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526072 0.82 POLB (0.43) MEN1KMT2APOLBTSHRCARM1
SCHEMBL31752066 0.81 TP53 (0.37) POLBTSHRAAK1LMNAKDM4E
SCHEMBL31753130 0.81 CTSL (0.40) CTSS
SCHEMBL33526516 0.79 HSP90AA1 (0.38) MEN1KMT2APOLBTSHRCARM1
SCHEMBL31752097 0.77 CTSK (0.34) POLBTSHRCARM1KDM4ECTSS
SCHEMBL33526756 0.75 NPSR1 (0.39) POLBTSHRALDH1A1NPSR1
SCHEMBL16533483 0.71 MEN1 (0.58) MEN1KMT2APOLBSMN1; SMN2LMNA
SCHEMBL18573922 0.71 MEN1 (0.58) MEN1KMT2APOLBAAK1MGLL
SCHEMBL18573921 0.71 MEN1 (0.54) MEN1KMT2APOLBAAK1SMN1; SMN2
SCHEMBL8282485 0.70 MEN1 (0.58) MEN1KMT2APOLBSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 MEN1 3404/4885KMT2A 3887/4885POLB 4745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.