SCHEMBL33526756

SCHEMBL33526756

CC(C)(Cn1nc(C(F)(F)F)cc1C1CCN1C(=O)OCc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.39
PDE4B Q07343 1/20 0.39
PDK1 Q15118 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK3 Q15120 1/20 0.38
PDK4 Q16654 1/20 0.38
AADAT Q8N5Z0 1/20 0.38
SIGMAR1 Q99720 4/20 0.38
TMEM97 Q5BJF2 3/20 0.38
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33525928 0.86 PDK1 (0.42) NPSR1PDK1PDK2PDK3PDK4
SCHEMBL33526676 0.78 POLB (0.48) POLB
SCHEMBL31753684 0.76 POLB (0.44) POLB
SCHEMBL33527410 0.75 POLB (0.44) POLB
SCHEMBL33526072 0.75 POLB (0.43) POLBTSHR
SCHEMBL33525657 0.75 MEN1 (0.45) NPSR1ALDH1A1POLBTSHR
SCHEMBL33526516 0.73 HSP90AA1 (0.38) POLBTSHR
SCHEMBL31752066 0.71 TP53 (0.37) POLBTSHR
SCHEMBL31753407 0.70 GRN (0.41) POLBTSHR
SCHEMBL33527256 0.70 LMNA (0.48) NPSR1ALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 NPSR1 109/4885PDE4B 1755/4885PDK1 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.