SCHEMBL33526103

SCHEMBL33526103

CC(C)(Cn1ccc(F)n1)NC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.40
LATS1 O95835 1/20 0.35
AAK1 Q2M2I8 5/20 0.34
DRD2 P14416 3/20 0.33
SCN9A Q15858 1/20 0.33
CYP17A1 P05093 2/20 0.32
ATR Q13535 1/20 0.32
APLNR P35414 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
CTSL P07711 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
MAPK14 Q16539 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526594 0.85 LATS1 (0.35) LATS1AAK1DRD2ATRPTGDR2
SCHEMBL31753566 0.84 LMNA (0.43) ARNPC1RAB9AKMT2A
SCHEMBL28440709 0.83 AR (0.45) ARLATS1SCN9ANPC1RAB9A
SCHEMBL31752681 0.72 AR (0.41) ARLATS1SCN9A
SCHEMBL20076210 0.71 AR (0.49) ARAAK1
SCHEMBL23138106 0.70 AR (0.41) AR
SCHEMBL26658256 0.70 AR (0.39) ARLATS1AAK1MEN1NPC1
SCHEMBL23229673 0.70 AR (0.39) ARLATS1AAK1MEN1KMT2A
SCHEMBL33527256 0.68 LMNA (0.48) GAAKMT2A
SCHEMBL33526119 0.68 AAK1 (0.37) LATS1AAK1APLNRCTSLPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 AR 465/4885LATS1 3736/4885AAK1 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.