SCHEMBL33526119

SCHEMBL33526119

CC(C)(Cn1nc(Br)cc1Br)NC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 9/20 0.37
LATS1 O95835 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
APLNR P35414 1/20 0.32
PTGER1 P34995 2/20 0.32
CTSL P07711 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
MAPK14 Q16539 1/20 0.32
SUV39H2 Q9H5I1 1/20 0.31
CYP2C9 P11712 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30622946 0.86 AAK1 (0.34) AAK1LATS1NPC1RAB9ARECQL
SCHEMBL26645756 0.85 AAK1 (0.34) AAK1LATS1CTSLSUV39H2
SCHEMBL31752066 0.85 TP53 (0.37) AAK1APLNRCYP2C9
SCHEMBL25345566 0.81 ALDH1A1 (0.41) SUV39H2KMT2AMEN1HTTALDH1A1
SCHEMBL33526442 0.80 AAK1 (0.37) AAK1LATS1PTGER1PTGDR2CYP2C9
SCHEMBL26645574 0.77 LATS1 (0.32) LATS1
SCHEMBL31696666 0.77 BACE1 (0.34)
SCHEMBL20517781 0.76 KDM4E (0.37) CYP2C9KMT2AALDH1A1
SCHEMBL33527256 0.73 LMNA (0.48) CYP2C9KMT2AALDH1A1
SCHEMBL33526182 0.71 L3MBTL1 (0.39) CTSLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 AAK1 2749/4885LATS1 3736/4885NPC1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.