SCHEMBL33526163

SCHEMBL33526163

OCCc1cc(F)cc(F)c1Br

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.36
PTPN1 P18031 1/20 0.30
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13068931 0.83 GPR84 (0.38) GPR84PTPN1RIPK1
SCHEMBL29629074 0.83 GPR84 (0.38) GPR84PTPN1RIPK1
SCHEMBL20017710 0.79 GPR84 (0.33) GPR84
SCHEMBL1967720 0.78 RIPK1 (0.42) GPR84RIPK1
SCHEMBL15286871 0.77 FFAR1 (0.45)
SCHEMBL17006161 0.77 ERN1 (0.41) RIPK1
SCHEMBL28540474 0.76 GPR84 (0.39) GPR84
SCHEMBL28816037 0.74 GPR84 (0.38) GPR84
SCHEMBL15286872 0.72 EGFR (0.38)
SCHEMBL25327645 0.71 TDP1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 GPR84 86/4885PTPN1 1232/4885RIPK1 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.