Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13068931 | 0.79 | GPR84 (0.38) | GPR84CES2CES1 | |
| SCHEMBL28816037 | 0.79 | GPR84 (0.38) | GPR84 | |
| SCHEMBL29629074 | 0.79 | GPR84 (0.38) | GPR84CES2CES1 | |
| SCHEMBL489929 | 0.78 | RIPK1 (0.41) | GPR84CES2CES1 | |
| SCHEMBL919665 | 0.76 | KDM1A (0.42) | GPR84CES2CES1 | |
| SCHEMBL33526163 | 0.76 | GPR84 (0.36) | GPR84 | |
| SCHEMBL5162621 | 0.74 | RAPGEF4 (0.32) | GPR84 | |
| SCHEMBL20594895 | 0.74 | GPR84 (0.31) | GPR84 | |
| SCHEMBL6553272 | 0.73 | KDM1A (0.41) | GPR84CES2CES1 | |
| SCHEMBL24357673 | 0.72 | KDM1A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349983-B | Dihydroimidazopyrazinone derivatives useful for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-108349983-A | The useful glyoxalidine for the treatment of cancer and pyrazinone derivatives | 阿斯利康(瑞典)有限公司 | 2018-07-31 | — | — | CN | disclosed |