SCHEMBL33526446

SCHEMBL33526446

COc1cc2c(cnn2C)[n+]([O-])c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.31
DYRK1A Q13627 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23210999 0.76 NPBWR1 (0.48)
SCHEMBL33526469 0.76 APP (0.31)
SCHEMBL31662414 0.76 HSD17B10 (0.32)
SCHEMBL23210812 0.75 ACSS2 (0.37)
SCHEMBL31752570 0.72 CYP11B2 (0.36)
SCHEMBL23210874 0.67 ACSS2 (0.33)
SCHEMBL23236620 0.67 GRIN1 (0.38)
SCHEMBL13113212 0.67 HTR2A (0.59) HTR2AHTR2CHTR2B
SCHEMBL33526077 0.67 GRIN1 (0.38)
SCHEMBL22660499 0.66 GRM2 (0.37) MAOADYRK1AHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 MAOA 3712/4885DYRK1A 1039/4885HTR2A 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.