SCHEMBL33526846

SCHEMBL33526846

CN(C)C(=O)c1cc(C(F)(F)F)nn1CC(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.39
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
LMNA P02545 1/20 0.34
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CNR2 P34972 3/20 0.32
CNR1 P21554 2/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
CTSL P07711 1/20 0.32
KLKB1 P03952 1/20 0.32
F10 P00742 1/20 0.31
VNN1 O95497 1/20 0.31
AURKA O14965 1/20 0.31
CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31753407 0.87 GRN (0.41) TP53L3MBTL1KDM4ENPC1LMNA
SCHEMBL31753527 0.86 TP53 (0.38) TP53L3MBTL1KDM4ENPC1LMNA
SCHEMBL31752997 0.86 TP53 (0.36) TP53L3MBTL1KDM4ELMNAALDH1A1
SCHEMBL33525658 0.83 HPGD (0.41) TP53L3MBTL1KDM4ELMNAALDH1A1
SCHEMBL31752137 0.83 CNR2 (0.33) TP53L3MBTL1KDM4ELMNAALDH1A1
SCHEMBL33527256 0.82 LMNA (0.48) TP53L3MBTL1KDM4ELMNAALDH1A1
SCHEMBL31752066 0.81 TP53 (0.37) TP53L3MBTL1KDM4ELMNACYP3A4
SCHEMBL33526182 0.81 L3MBTL1 (0.39) TP53L3MBTL1KDM4ELMNAALDH1A1
SCHEMBL33526676 0.80 POLB (0.48) CNR2CNR1POLB
SCHEMBL31752359 0.80 TP53 (0.36) TP53L3MBTL1KDM4ELMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 CARM1 1856/4885TP53 4863/4885L3MBTL1 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.