SCHEMBL33525658

SCHEMBL33525658

CCOC(=O)c1cc(C(F)(F)F)nn1CC(C)(C)NC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.41
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 1/20 0.34
CNR2 P34972 3/20 0.34
CNR1 P21554 2/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
SYK P43405 1/20 0.33
AAK1 Q2M2I8 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
PTPRB P23467 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31753527 0.90 TP53 (0.38) HPGDLMNAALDH1A1TP53L3MBTL1
SCHEMBL31753407 0.86 GRN (0.41) LMNATP53L3MBTL1POLBKDM4E
SCHEMBL31752997 0.85 TP53 (0.36) LMNAALDH1A1TP53L3MBTL1POLB
SCHEMBL33527256 0.84 LMNA (0.48) HPGDLMNAALDH1A1TP53L3MBTL1
SCHEMBL33526846 0.83 CARM1 (0.39) LMNAALDH1A1TP53L3MBTL1POLB
SCHEMBL27341116 0.83 HPGD (0.43) HPGDLMNAALDH1A1TP53L3MBTL1
SCHEMBL31752066 0.81 TP53 (0.37) LMNATP53L3MBTL1POLBKDM4E
SCHEMBL33526182 0.80 L3MBTL1 (0.39) LMNAALDH1A1TP53L3MBTL1POLB
SCHEMBL31752359 0.79 TP53 (0.36) HPGDLMNATP53L3MBTL1POLB
SCHEMBL33526694 0.79 TP53 (0.36) HPGDLMNATP53L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 HPGD 1827/4885LMNA 2816/4885ALDH1A1 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.