SCHEMBL33526945

SCHEMBL33526945

COc1cc2c(nc1Cl)c(Cl)nn2C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.34
PDE10A Q9Y233 3/20 0.33
PDE2A O00408 2/20 0.33
PGK1 P00558 2/20 0.33
ALDH1A1 P00352 4/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
NQO2 P16083 1/20 0.32
GAA P10253 1/20 0.32
NPC1 O15118 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
BRD4 O60885 1/20 0.30
BRD2 P25440 1/20 0.30
BRD3 Q15059 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33527615 0.85 PDE2A (0.36) S100BPDE10APDE2APGK1ALDH1A1
SCHEMBL33525846 0.71 PGK1 (0.39) PDE10APGK1ALDH1A1KMT2AGAA
SCHEMBL31753213 0.71 ALDH1A1 (0.47) ALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL23236541 0.71 PGK1 (0.39) PDE10APGK1ALDH1A1KMT2AGAA
SCHEMBL18797087 0.69 BRD4 (0.46) ALDH1A1MAPTNQO2SMN1; SMN2KDM4E
SCHEMBL33527018 0.69 GRIN1 (0.34) PDE10APDE2A
SCHEMBL33526544 0.69 GRM4 (0.32) PDE10APDE2A
SCHEMBL33525628 0.68
SCHEMBL23210776 0.67 MTNR1A (0.36) ALDH1A1MAPTGAANPC1SMN1; SMN2
SCHEMBL23537901 0.67 ENPP1 (0.50) PGK1ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 S100B 4827/4885PDE10A 1660/4885PDE2A 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.