SCHEMBL33527402

SCHEMBL33527402

CC(C)(N)Cc1ccc(F)cc1Br

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.36
SLC6A2 P23975 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35
IDO1 P14902 4/20 0.35
AGXT P21549 2/20 0.35
P2RX7 Q99572 2/20 0.34
PKM P14618 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
HRH1 P35367 1/20 0.33
HTR2B P41595 1/20 0.33
CHRNA4 P43681 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KMT2A Q03164 1/20 0.33
RIPK1 Q13546 2/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28981934 0.81 PKM (0.37) NR3C1IDO1AGXTP2RX7PKM
SCHEMBL564877 0.81 IDO1 (0.50) SLC6A2TAAR1IDO1AGXTHTR2A
SCHEMBL564873 0.79 SLC6A2 (0.36) NR3C1SLC6A2TAAR1IDO1AGXT
SCHEMBL31490495 0.79 IDO1 (0.38) NR3C1IDO1AGXTP2RX7PKM
SCHEMBL564609 0.78 NPC1 (0.43) NR3C1SLC6A2P2RX7HTR2ASLC6A4
SCHEMBL30005666 0.74 PKM (0.42) IDO1AGXTP2RX7PKMKMT2A
SCHEMBL3711398 0.74 PKM (0.42) IDO1AGXTP2RX7PKMKMT2A
SCHEMBL3910128 0.74 MPO (0.44) TAAR1IDO1AGXTP2RX7PKM
Hydrochloric Acid SCHEMBL856646 0.72 MPO (0.43) TAAR1IDO1AGXTP2RX7PKM
SCHEMBL15638695 0.72 TAAR1 (0.50) NR3C1SLC6A2TAAR1IDO1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 NR3C1 115/4885SLC6A2 2245/4885TAAR1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.