SCHEMBL33527410

SCHEMBL33527410

CN1CCC(c2cc(C(F)(F)F)nn2CC(C)(C)NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
GRIN1 Q05586 4/20 0.37
GRIN2A Q12879 4/20 0.37
GRIA2 P42262 1/20 0.36
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
SSTR4 P31391 5/20 0.35
GAA P10253 1/20 0.35
PTGS2 P35354 1/20 0.34
SSTR1 P30872 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33526676 0.93 POLB (0.48) POLBGRIN1GRIN2AGRIA2CNR1
SCHEMBL31753684 0.91 POLB (0.44) POLBGRIN1GRIN2AGRIA2CNR1
SCHEMBL33527256 0.78 LMNA (0.48) POLBGAA
SCHEMBL31752066 0.77 TP53 (0.37) POLBCNR2GAA
SCHEMBL33526182 0.76 L3MBTL1 (0.39) POLBCNR2GAA
SCHEMBL31753407 0.76 GRN (0.41) POLBCNR1CNR2
Hydrochloric Acid SCHEMBL33526972 0.76 POLB (0.42) POLBGRIN1GRIN2AGRIA2GAA
SCHEMBL31753527 0.76 TP53 (0.38) POLBCNR1CNR2GAA
SCHEMBL33526694 0.76 TP53 (0.36) POLBCNR2GAA
SCHEMBL31752359 0.76 TP53 (0.36) POLBCNR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GPR119 POLB 4745/4885GRIN1 1493/4885GRIN2A 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.