Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369074 | 0.76 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2HIF1A | |
| SCHEMBL7316714 | 0.76 | SMN1; SMN2 (0.50) | L3MBTL1SMN1; SMN2HIF1A | |
| SCHEMBL31522777 | 0.74 | L3MBTL1 (0.42) | L3MBTL1AKT1SMN1; SMN2HIF1APPARG | |
| SCHEMBL8366831 | 0.74 | L3MBTL1 (0.42) | L3MBTL1AKT1SMN1; SMN2HIF1APPARG | |
| SCHEMBL25182230 | 0.74 | L3MBTL1 (0.42) | L3MBTL1AKT1SMN1; SMN2HIF1APPARG | |
| SCHEMBL18248193 | 0.73 | L3MBTL1 (0.38) | L3MBTL1AKT1SMN1; SMN2HIF1APPARG | |
| SCHEMBL30887346 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1APPARGPPARA | |
| SCHEMBL3736878 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1APPARGPPARA | |
| SCHEMBL29112713 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1APPARGPPARA | |
| SCHEMBL17559223 | 0.72 | AKT1 (0.40) | L3MBTL1AKT1SMN1; SMN2HIF1APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260091118-A1 | Methods for Preparation and Use of BacPROTACs for Targeted Protein Degradation in Mycobacteria and Other Bacteria | WASHINGTON UNIVERSITY (US) | 2026-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260091118-A1 | Methods for Preparation and Use of BacPROTACs for Targeted Protein Degradation in Mycobacteria and Other Bacteria | CLPP, DNPEP, NPEPPS | L3MBTL1 2713/4885AKT1 4502/4885SMN1; SMN2 3630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.