Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.40 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.40 |
| ▸ | GART | P22102 | 1/20 | 0.40 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.40 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.40 |
| ▸ | TUBB | P07437 | 5/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335909 | 0.89 | HDAC3 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL336014 | 0.84 | ABL1 (0.41) | MAPTHDAC6F7F3TRPV1 | |
| SCHEMBL335501 | 0.82 | NPC1 (0.43) | HDAC3HDAC1HDAC8MAPTPKM | |
| SCHEMBL336443 | 0.81 | SMN1; SMN2 (0.43) | KDM4EMAPT | |
| SCHEMBL335834 | 0.81 | RAB9A (0.42) | HDAC1HDAC8KDM4EMEN1ALDH1A1 | |
| SCHEMBL335576 | 0.80 | ABL1 (0.43) | LMNAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL336039 | 0.80 | DHFR (0.41) | MAPTF7F3 | |
| SCHEMBL335551 | 0.79 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2AHDAC2 | |
| SCHEMBL15282285 | 0.79 | ACP1 (0.46) | LMNAKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15282212 | 0.79 | ACP1 (0.46) | LMNAKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |