Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3769982 | 1.00 | LMNA (0.31) | LMNACHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3354015 | 0.77 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5616377 | 0.75 | BRD4 (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL5616492 | 0.75 | CHRNB2 (0.34) | LMNACHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL1775471 | 0.74 | PDCD1 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3353027 | 0.73 | — | — | |
| SCHEMBL17415183 | 0.73 | MEN1 (0.30) | LMNA | |
| Hydrochloric Acid SCHEMBL1686878 | 0.71 | EDNRB (0.35) | LMNA | |
| Hydrochloric Acid SCHEMBL3352582 | 0.69 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7938880 | 0.68 | CHRNB2 (0.33) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410231-B2 | Production process of olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100029868-A1 | PRODUCTION PROCESS OF OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20080234450-A1 | DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-25 | — | — | US | disclosed |
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |