Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15321069 | 0.93 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL18547374 | 0.91 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL3358898 | 0.85 | KMT2A (0.52) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL606162 | 0.85 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL29847375 | 0.85 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL29848622 | 0.85 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAHTTRAB9A | |
| SCHEMBL13537228 | 0.85 | MAPT (0.50) | MAPTALDH1A1NPSR1HTTKMT2A | |
| SCHEMBL28612388 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL3358343 | 0.85 | ALOX15 (0.55) | MAPTALDH1A1NPSR1HTTKMT2A | |
| SCHEMBL15319957 | 0.84 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |