Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22382467 | 0.92 | KMT2A (0.60) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4124929 | 0.88 | ALOX15 (0.65) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL22725419 | 0.87 | KMT2A (0.54) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL22382328 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3353065 | 0.85 | MAPT (0.51) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3353106 | 0.82 | ALOX15 (0.63) | LMNAALOX15PTGER4 | |
| SCHEMBL15319957 | 0.82 | MAPT (0.66) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL15321361 | 0.82 | HCAR3 (0.68) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL19245337 | 0.82 | ALOX15 (0.59) | RAB9AALOX15PTGER4 | |
| SCHEMBL13537290 | 0.81 | ALOX15 (0.52) | ALDH1A1MAPTALOX15PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |