SCHEMBL33530786

SCHEMBL33530786

CCC(=O)NCCc1ccccc1Br

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
MTNR1A P48039 4/20 0.50
MTNR1B P49286 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
RIPK1 Q13546 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30259906 0.83 RIPK1 (0.62) CA12CA1CA2CA9RIPK1
SCHEMBL2905338 0.83 RIPK1 (0.62) CA12CA1CA2CA9RIPK1
SCHEMBL29686650 0.83 MTNR1A (0.61) TAAR1MTNR1AMTNR1B
SCHEMBL533866 0.83 MTNR1A (0.61) TAAR1MTNR1AMTNR1B
SCHEMBL33532174 0.83 SPR (0.52) TAAR1MTNR1AMTNR1BCA12CA1
SCHEMBL27586477 0.81 MTNR1A (0.52) MTNR1AMTNR1BSMN1; SMN2
SCHEMBL14242720 0.81 TP53 (0.52) MTNR1AMTNR1BSMN1; SMN2
SCHEMBL3638162 0.81 TAAR1 (0.56) TAAR1MTNR1AMTNR1BCA12CA1
SCHEMBL555438 0.80 ALDH1A1 (0.49) TAAR1MTNR1AMTNR1BCA12CA1
SCHEMBL14241867 0.80 TAAR1 (0.56) TAAR1MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LTD (GB) 2026-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION BCL9L, RBBP9, BRD9 TAAR1 1518/4885MTNR1A 3557/4885MTNR1B 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.