Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348171 | 0.90 | TAAR1 (0.53) | MC4RCNR1GAAKCNH2TAAR1 | |
| SCHEMBL3410485 | 0.89 | MC4R (0.43) | MC4RCNR1KCNH2TAAR1GLA | |
| SCHEMBL3353146 | 0.88 | TAAR1 (0.47) | MC4RKCNH2TAAR1ALDH1A1NPC1 | |
| SCHEMBL3410126 | 0.88 | MC4R (0.57) | MC4RGAAKCNH2TAAR1NPC1 | |
| SCHEMBL3353041 | 0.87 | CNR1 (0.55) | MC4RCNR1GAAKCNH2TAAR1 | |
| SCHEMBL3352433 | 0.86 | CNR1 (0.46) | MC4RCNR1KCNH2RAB9AROCK2 | |
| SCHEMBL3353044 | 0.85 | KCNH2 (0.46) | MC4RCNR1GAAKCNH2TAAR1 | |
| SCHEMBL3353136 | 0.85 | TAAR1 (0.50) | MC4RCNR1GAATAAR1GLA | |
| SCHEMBL22179089 | 0.81 | MC4R (0.63) | MC4RCNR1GAATAAR1GLA | |
| SCHEMBL22179092 | 0.81 | MC4R (0.63) | MC4RCNR1GAATAAR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |