Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MC4R | P32245 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353041 | 0.90 | CNR1 (0.55) | KCNH2MC4RCNR1GLATAAR1 | |
| SCHEMBL3346608 | 0.89 | KCNH2 (0.50) | KCNH2MC4RCNR1TAAR1ALDH1A1 | |
| SCHEMBL3353136 | 0.88 | TAAR1 (0.50) | MC4RCNR1GLATAAR1ALDH1A1 | |
| SCHEMBL3353235 | 0.85 | ROCK2 (0.49) | KCNH2MC4RCNR1ALDH1A1ROCK2 | |
| SCHEMBL3353112 | 0.85 | MC4R (0.43) | KCNH2MC4RCNR1GLATAAR1 | |
| SCHEMBL3346495 | 0.84 | DPP4 (0.50) | MC4RCNR1GLATAAR1ALDH1A1 | |
| SCHEMBL22179089 | 0.83 | MC4R (0.63) | MC4RCNR1GLATAAR1ALDH1A1 | |
| SCHEMBL22179092 | 0.83 | MC4R (0.63) | MC4RCNR1GLATAAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22160598 | 0.82 | MC4R (0.61) | MC4RCNR1GLATAAR1ALDH1A1 | |
| SCHEMBL2229909 | 0.79 | MC4R (0.63) | KCNH2MC4RALDH1A1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |