Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353041 | 0.92 | CNR1 (0.55) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL3353142 | 0.88 | MC4R (0.62) | TAAR1GLAALDH1A1MC4RMAPT | |
| SCHEMBL3353044 | 0.88 | KCNH2 (0.46) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL3346495 | 0.85 | DPP4 (0.50) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL22179092 | 0.85 | MC4R (0.63) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL22179089 | 0.85 | MC4R (0.63) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL3353112 | 0.85 | MC4R (0.43) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL3347960 | 0.85 | CNR1 (0.52) | TAAR1GLACNR1ALDH1A1MC4R | |
| Hydrochloric Acid SCHEMBL22160598 | 0.84 | MC4R (0.61) | TAAR1GLACNR1ALDH1A1MC4R | |
| SCHEMBL3346679 | 0.81 | MC4R (0.59) | TAAR1GLAALDH1A1MC4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |