Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358883 | 0.91 | CTSB (0.59) | CTSBHRH3MAPTALDH1A1KCNJ1 | |
| SCHEMBL3357630 | 0.88 | ALDH1A1 (0.53) | CTSBHRH3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3356418 | 0.88 | HTR6 (0.54) | CTSBLMNASMN1; SMN2HTR6 | |
| SCHEMBL3353183 | 0.85 | CTSB (0.53) | CTSBHRH3MAPTALDH1A1KCNJ1 | |
| SCHEMBL3357604 | 0.81 | CTSB (0.56) | CTSBMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL3352554 | 0.80 | KMT2A (0.51) | CTSBMAPTALDH1A1KCNJ1LMNA | |
| SCHEMBL3352978 | 0.79 | CACNB4 (0.56) | CTSBHRH3MAPTALDH1A1LMNA | |
| SCHEMBL3358110 | 0.79 | HRH3 (0.55) | HRH3MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL13537253 | 0.79 | HRH3 (0.48) | CTSBHRH3MAPTALDH1A1KCNJ1 | |
| SCHEMBL3356257 | 0.78 | CACNB4 (0.58) | CTSBHRH3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |