Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350808 | 0.89 | TAAR1 (0.53) | CNR1HTTGLATAAR1ALDH1A1 | |
| SCHEMBL3346278 | 0.86 | CNR1 (0.57) | CNR1SLC6A4HTR2CHTR2BCA1 | |
| SCHEMBL3349714 | 0.85 | MC4R (0.57) | CNR1GLATAAR1ALDH1A1MAPT | |
| SCHEMBL3347960 | 0.84 | CNR1 (0.52) | CNR1CA1CA2HTTROCK2 | |
| SCHEMBL3352433 | 0.84 | CNR1 (0.46) | CNR1CA1CA2ROCK2ROCK1 | |
| SCHEMBL3350852 | 0.82 | MC4R (0.37) | ROCK2MAPTMC4R | |
| SCHEMBL3353235 | 0.80 | ROCK2 (0.49) | CNR1CA1CA2ROCK2ALDH1A1 | |
| SCHEMBL3350733 | 0.80 | CNR1 (0.48) | CNR1CA1CA2HTTGLA | |
| SCHEMBL3346689 | 0.80 | POLB (0.50) | HTTROCK2ROCK1 | |
| SCHEMBL3350885 | 0.80 | TAAR1 (0.47) | CNR1TAAR1ALDH1A1MAPTMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |