Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359089 | 0.93 | HTR7 (0.43) | HTR7HTR6KDM1APRKCIHTR2C | |
| SCHEMBL31324655 | 0.84 | HTR7 (0.46) | HTR7HTR6KDM1APRKCIHTR2C | |
| SCHEMBL13537343 | 0.80 | HTR7 (0.38) | HTR7HTR6KDM1ACYP1A2CYP2D6 | |
| SCHEMBL15712192 | 0.80 | HTR7 (0.43) | HTR7HTR6 | |
| SCHEMBL3354696 | 0.78 | HTR7 (0.58) | HTR7HTR6CYP1A2CYP2D6 | |
| SCHEMBL7808872 | 0.77 | NR1H2 (0.44) | — | |
| SCHEMBL31735705 | 0.74 | PRKCI (0.46) | HTR7PRKCI | |
| SCHEMBL3354629 | 0.74 | HTR6 (0.48) | HTR6CYP1A2CYP2D6 | |
| SCHEMBL6300524 | 0.73 | PRKCI (0.47) | HTR7HTR6PRKCIHTR2CHTR2A | |
| SCHEMBL13537316 | 0.73 | HTR7 (0.41) | HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |