SCHEMBL31735705

SCHEMBL31735705

CN1CCC(CCn2ccc3cc(N)ccc32)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.46
HTR7 P34969 1/20 0.41
EGFR P00533 2/20 0.41
ACHE P22303 1/20 0.39
LCK P06239 1/20 0.38
KIT P10721 1/20 0.38
SRC P12931 1/20 0.38
KDR P35968 1/20 0.38
NTSR1 P30989 1/20 0.38
BRPF1 P55201 1/20 0.37
NOS3 P29474 4/20 0.37
NOS1 P29475 4/20 0.37
NOS2 P35228 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18539228 0.87 PRKCI (0.46) PRKCIHTR7EGFRACHELCK
SCHEMBL15604166 0.84 PRKCI (0.43) PRKCIEGFRLCKKITSRC
SCHEMBL15521929 0.81 ALDH1A1 (0.45)
SCHEMBL12367568 0.79 NOS3 (0.56) PRKCINOS3NOS1NOS2
SCHEMBL31461321 0.79 HTR7 (0.64) PRKCIHTR7NTSR1NOS3NOS1
SCHEMBL31735794 0.79 ACHE (0.57) HTR7ACHE
SCHEMBL2263565 0.78 NOS3 (0.56) PRKCIHTR7NOS3NOS1NOS2
SCHEMBL3359089 0.78 HTR7 (0.43) PRKCIHTR7
SCHEMBL6300524 0.75 PRKCI (0.47) PRKCIHTR7EGFRNTSR1BRPF1
SCHEMBL3650822 0.75 PRKCI (0.59) PRKCIEGFRNTSR1BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed