Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354480 | 0.83 | HTR7 (0.49) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL3352715 | 0.79 | HTR7 (0.59) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL3352886 | 0.79 | MAPT (0.42) | ALDH1A1LMNAKMT2ACYP2D6SMN1; SMN2 | |
| SCHEMBL3358037 | 0.78 | ALDH1A1 (0.40) | HTR7ALDH1A1SIGMAR1LTA4HPTGS1 | |
| SCHEMBL6069457 | 0.77 | CNR1 (0.50) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL1121934 | 0.75 | HTR7 (0.82) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL13537296 | 0.74 | PDE4A (0.37) | SIGMAR1CNR1CNR2 | |
| SCHEMBL1121912 | 0.74 | HTR7 (0.80) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL4525372 | 0.74 | HTR7 (0.80) | HTR7HRH3ALDH1A1LMNAMEN1 | |
| SCHEMBL2075531 | 0.73 | HTR7 (0.67) | HTR7HRH3ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |