Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735677 | 0.90 | F2RL3 (0.46) | MAPTLMNATDP1F2RL3KMT2A | |
| SCHEMBL3352477 | 0.82 | ALDH1A1 (0.52) | MAPTLMNATDP1F2RL3KMT2A | |
| SCHEMBL3354060 | 0.81 | CNR2 (0.47) | MAPTKMT2ACNR2ALDH1A1 | |
| SCHEMBL3352610 | 0.81 | F2RL3 (0.39) | MAPTLMNATDP1F2RL3KMT2A | |
| SCHEMBL3354062 | 0.80 | KMT2A (0.41) | MAPTF2RL3KMT2ASMN1; SMN2ASH1L | |
| SCHEMBL3353415 | 0.79 | HTR7 (0.51) | MAPTLMNAKMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL3356042 | 0.78 | CACNB4 (0.52) | LMNAKMT2ASMN1; SMN2CYP2D6HTT | |
| SCHEMBL3354509 | 0.77 | CACNB4 (0.54) | LMNATDP1KMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL3351079 | 0.77 | HTR6 (0.48) | MAPTSMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL3351946 | 0.77 | DYRK1A (0.38) | KMT2AASH1LCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |