Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353415 | 0.83 | HTR7 (0.51) | HTR7ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3352477 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL3352715 | 0.77 | HTR7 (0.59) | HTR7ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL13537231 | 0.77 | CNR2 (0.42) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL12642972 | 0.77 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL12642921 | 0.76 | CNR2 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL3353614 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1121934 | 0.74 | HTR7 (0.82) | HTR7ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL3352006 | 0.73 | MAPT (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1121912 | 0.73 | HTR7 (0.80) | HTR7ALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |