Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352477 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL3352006 | 0.86 | MAPT (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL31735677 | 0.82 | F2RL3 (0.46) | KMT2ASMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL2814624 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAMAPTPOLB | |
| SCHEMBL3357593 | 0.80 | CNR1 (0.47) | ALDH1A1KMT2AMEN1MAPTF2RL3 | |
| SCHEMBL379545 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL3357597 | 0.78 | F2RL3 (0.44) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL29277388 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL13537207 | 0.77 | POLB (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTPOLB | |
| SCHEMBL1518274 | 0.76 | POLB (0.71) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |