Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353763 | 0.86 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL379545 | 0.82 | ALDH1A1 (0.59) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29277388 | 0.80 | ALDH1A1 (0.64) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8271779 | 0.78 | PTGER4 (0.47) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL8238735 | 0.78 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL3352477 | 0.76 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1791581 | 0.76 | BCHE (0.60) | ALDH1A1ACHEPOLBL3MBTL1 | |
| SCHEMBL15525180 | 0.75 | LMNA (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6764463 | 0.75 | KMT2A (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28592168 | 0.75 | ICMT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |