Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353763 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3352886 | 0.82 | MAPT (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL3354060 | 0.80 | CNR2 (0.47) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3354480 | 0.80 | HTR7 (0.49) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3353614 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3352610 | 0.79 | F2RL3 (0.39) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL23855046 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL3354062 | 0.78 | KMT2A (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL13537208 | 0.77 | POLB (0.46) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL1518274 | 0.76 | POLB (0.71) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |