Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347186 | 0.82 | GRM5 (0.37) | GRM5TRPV3 | |
| SCHEMBL103337 | 0.79 | GRM5 (0.42) | GRM5TRPV3 | |
| SCHEMBL103656 | 0.79 | GRM5 (0.42) | GRM5TRPV3 | |
| SCHEMBL103768 | 0.79 | CHRNB2 (0.43) | GRM5TRPV3 | |
| SCHEMBL5258543 | 0.77 | GRM5 (0.66) | GRM5 | |
| SCHEMBL14207818 | 0.74 | GRM5 (0.42) | GRM5 | |
| SCHEMBL101806 | 0.74 | GRM5 (0.38) | GRM5 | |
| SCHEMBL28020770 | 0.73 | CTSS (0.40) | — | |
| SCHEMBL3354041 | 0.73 | KCNH2 (0.33) | — | |
| SCHEMBL102431 | 0.72 | GRM5 (0.48) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |